Mucoactive phytopreparations with ivy extract in pediatrics: efficacy, safety and economic feasibility


  • O.Ya. Mishchenko Institute for Advanced Training of Pharmacy Specialists of the National University of Pharmacy, Ukraine


mucoactive phytopreparations, ivy extract, efficiency, safety, economic feasibility


Acute bronchitis is an infectious inflammatory disease of the lower respiratory tract which occurs at any age. The main symptom of acute bronchitis is non-productive (dry) or productive (wet) cough. The main goal in treating acute bronchitis with productive cough is to increase expectoration, including with the help of mucoactive drugs. In clinical practice, herbal medicines are increasingly used to eliminate symptoms of the disease and to suppress inflammation. The advantage of herbal coughs medicines is that various compounds of herbal ingredients are able to enhance the desired effects and neutralize side effects. Among the numerous expectorant herbal preparations, only a few, namely, preparations of common ivy, thyme and primrose, have the most complex effect: they increase mucus secretion and motility, reduce respiratory tract tone and inhibit inflammation. A comparative pharmacoeconomic analysis of medicines based on ivy extract in the form of syrup which are available on the pharmaceutical market showed that treatment with Gederin Ivy Syrup is the optimal from a pharmacoeconomic point of view. The combination of such effects of ivy extract in the preparation Gederin Ivy, as expectorant (mucokinetic and secretolytic), bronchospasmolytic and anti-inflammatory, predetermines its pronounced clinical efficacy for the treatment of cough, as well as good tolerance, allow it to be widely used in the complex therapy of bronchitis in pediatric practice.



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