Features of the treatment of secretory evacuation disorders in acute bronchitis in children with impaired respiratory function

Authors

  • L.S. Ovcharenko SI «Zaporizhzhya Medical Academy of Postgraduate Education of the Ministry of Health of Ukraine», Ukraine
  • A.A. Vertehel SI «Zaporizhzhya Medical Academy of Postgraduate Education of the Ministry of Health of Ukraine», Ukraine
  • T.G. Andrienko SI «Zaporizhzhya Medical Academy of Postgraduate Education of the Ministry of Health of Ukraine», Ukraine
  • I.V. Samokhin SI «Zaporizhzhya Medical Academy of Postgraduate Education of the Ministry of Health of Ukraine», Ukraine
  • A.V. Kryazhev SI «Zaporizhzhya Medical Academy of Postgraduate Education of the Ministry of Health of Ukraine», Ukraine
  • D.N. Sheludko SI «Zaporizhzhya Medical Academy of Postgraduate Education of the Ministry of Health of Ukraine», Ukraine

Keywords:

children, bronchitis, spirography, treatment, thyme, ivy

Abstract

Objective: to increase the efficiency and safety of the treatment of the bronchi secretory-evacuation disorders in acute bronchitis with impaired respiratory function in children by using a medication with minimal effect on the cardiovascular system.

Materials and methods. Under observation were 60 children aged 6 to 11 years. 2 observation groups were formed (30 children in each group): 1st group — children receiving the Bronchipret® for 10 days with acute bronchitis with impaired respiratory function; 2nd group — children who do not receive the Bronchipret in acute bronchitis with impaired respiratory function.

Results. In the group of patients taking Bronchipret®, in addition to faster clinical dynamics, according to spirography, there was an improvement in the parameters of the external respiration function, characterizing the obstructive component of the obstruction of the air flow. After therapy with Bronchipret®, normalization of the functioning of the autonomic nervous system and the predominance of eutonia were observed against the background of a decrease in the number of registration of parasympathicotonia.

Conclusion. The good tolerance and safety of Bronchipret® during 7-day use in patients aged 6–11 years allows us to recommend this drug as a highly effective treatment for bronchi secretory-evacuation disorders in acute bronchitis in children.

The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of participating institution.

The informed consent of the patient was obtained for conducting the studies.

References

Bando H, Toyoda K, Hisa Y. (2016). Autonomic nervous system. Neuroanatomy and Neurophysiology of the Larynx. Springer, Tokyo.: 29-44. https://doi.org/10.1007/978-4-43; PMid:27866302

Eliseeva TI, Balabolkin II, Oshevenskiy LV, Prahov AV. (2009). Vegetativnaya regulyatsiya i variabelnost serdechnogo ritma u detey s bronhialnoy astmoy. Diagnosticheskie i prognosticheskie aspektyi. Monografiya. N. Novgorod: Izd-vo NNGU: 151.

Golden EP, Bryarly MA, Vernino S. (2018). Seronegative autoimmune autonomic neuropathy: a distinct clinical entity. Clinical Autonomic Research. 28(1): 115-123. https://doi.org/10.1007/s10286-017-0493-8; PMid:29280036

Hijikata T, Baba E, Shirokane K, Tsuchiya A, Nomura M. (2019). Subarachnoid hemorrhage due to de novo dissecting vertebral artery aneurysm in a patient with Guillain-Barre syndrome. Neurology and Clinical Neuroscience. 7(6): 341-343.; https://doi.org/10.1111/ncn3.12323

Nesterenko ZV. (2017). Recurrent bronchitis as a clinical variant of functional changes of the respiratory system in children. Pediatrician (St. Petersburg). 8(5): 44-48. https://doi.org/10.17816/PED8544-48

Ohotnikova OM, Duda LV. (2018). Bronhoobstruktsiya u detey: mnogoobrazie prichin, mnogolikost proyavleniy, slozhnost diagnostiki i vyibora individualnoy terapii. Pediatriya. Vostochnaya Evropa. 3: 440-458.

Reißenweber-Hewel H. (2017). Kampo-Medizin: Effektive und differenzierte Therapie bei Bronchitis. Deutsche Zeitschrift fur Akupunktur. 60(4): 46-49. https://doi.org/10.1016/S0415-6412(17)30129-7

Sebekina OV, Nenasheva NM. (2019). Antiholinergicheskie preparatyi v terapii bronhialnoy astmyi. Astma i allergiya. 1: 43-48.

Strelkova M, Senatorova G. (2018). Clinical and anamnestic features of the course of acute bronchitis in children. Inter collegas. 5(3): 143-147. https://doi.org/10.35339/ic.5.3.143-147

Yurenev GL, Yureneva-Thorzhevskaya TV. (2014). Bronhoobstruktivnyiy sindrom pri ostryih respiratornyih virusnyih infektsiyah: prichinyi i posledstviya. Prakticheskaya pulmonologiya. 1: 22–29.

Published

2020-09-28

Issue

Section

Practical doctor school