Infectious mononucleosis: the multiplicity of manifestations. a clinical case of a severe course of infectious mononucleosis in an infant

Abstract

Epstein–Barr virus infected more than 95% of the world's population. Difficulties in diagnosing this disease are caused by polymorphism of clinical manifestations.
Aim: on a clinical case, show the versatility of the manifestations of infectious mononucleosis in children.
Materials and methods. The clinical manifestations of an atypical severe course of infectious mononucleosis in a little child at the stage of hospital`s treatment are analyzed.
Results and conclusions. In a child with a nephropathy in anamnesis, infectious mononucleosis proceeded in a severe form with significant edematous syndrome and the absence of typical symptoms in the form of tonsillitis, a systemic inflammatory reaction, and lymphadenopathy. This made diagnosis difficult and required additional laboratory tests and the appointment of glucocorticosteroids in therapy.
The presented clinical case demonstrates the polymorphism of the clinical manifestations of the disease and the complexity of the diagnosis of severe cases of infectious mononucleosis due to the occurrence of atypical syndromes — polyserositis and edematous syndrome with the leveling of typical manifestations of the disease.
The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of an institution. The informed consent of the patient was obtained for conducting the studies.