Immunotropic activity of furamag in the treatment of recurrent urogenital tract infection in children
Keywords:children, urinary system, immunity, soluble furagin
AbstractThe aim: to increase the therapy effectiveness for recurrent urogenital tract infection in children through the use of the Furamag immunotropic properties.
Materials and methods. Under observation were 60 children aged 2 to 6 years in the period of exacerbation of recurrent urogenital tract infections. Two observation groups of 30 children each were formed. Children of the 1st group received Furamag for 7 days; group 2 children received cefixime also for 7 days.
Results. The immunotropic activity of Furamag was manifested by a decrease in the number of children with low indicators: phagocytic index and number, phagocytosis completion index, spontaneous NST-test index, stimulated with staphylococcus NST-test and its index, natural killer CD3-CD16+CD56+, low neutrophil myeloperoxidase activity, decreased serum IgG and IgA, urine secretory sIgA.
Conclusion. The dynamics of the innate and acquired immunity indicators showed the immunotropic activity of the 7-day of Furamag use, which improves the effectiveness of the treatment of recurrent urogenital tract infection in children.
The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee (LEC) of a participating institution. The informed consent of the patient was obtained for conducting the studies.
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