Regional characteristics of the incidence of congenital anomalies, deformities, and chromosomal disorders in newborns in Ukraine
DOI:
https://doi.org/10.15574/SP.2024.6(142).4249Keywords:
congenital anomalies, deformities, chromosomal disorders, incidence, genetic doctors, organization of medical-genetic servicesAbstract
Aim - to determine the regional characteristics of the incidence of the nosological group “Congenital Anomalies, Deformities, and Chromosomal Disorders” (Q00-Q99), considering the availability of genetic doctors and the pregnancy examination rate in Ukraine.
Materials and methods. Statistical data from were analyzed for the period 2012-2021. Incidence rates per 1,000 newborns for the nosological group “Congenital Anomalies, Deformities, and Chromosomal Disorders” (Q00-Q99) were calculated, along with the availability of genetic doctors per 1 million population and the examination rate per 100 pregnant women. Linear regression models were used for mathematical modeling, and model quality was evaluated using the coefficient of determination (R²). Correlation analysis was conducted among the indicators.
Results. Ukraine experienced a significant increase in the incidence of the group “Congenital Anomalies, Deformities, and Chromosomal Disorders” (Q00-Q99) from 2012 to 2021 (from 22.64‰ to 28.49‰), with a projected increase to 33.91‰ by 2026. Regional incidence variation ranged from 47.4‰ in the Volyn to 11.75‰ in the Kirovohrad Oblast. There is a decrease in the number of examined pregnant women per 100 pregnant women from 2012 to 2022 by -8.62%, from 39.84 per 100 pregnant women in 2012 to 36.41% in 2021.
Conclusions. The formed rating distribution of regions by morbidity indicators, provision of geneticists, the indicator of pregnant women examined in the medical genetic service and the growth rate of the indicated indicators from 2012 to 2021 indicates the best result in Poltava, Kirovohrad, Cherkasy Oblast and the existence of significant problems in the organization of medical genetic counseling in Zakarpattia, Lviv and Volyn Oblast.
No conflict of interests was declared by the authors.
References
Antipkin YuG, Marushko RV, Dudina EA. (2021). Evolution of infant mortality in Ukraine. Modern Pediatrics. Ukraine. 1(113): 6-14. https://doi.org/10.15574/SP.2021.113.6
International Organization for Migration. (2022). Ukraine Internal Displacement Report - General Population Survey Round 5. URL: http://surl.li/tudiw.
Ministerstvo rozvytku hromad ta terytorii Ukrainy. (2022). DSTU 1437:2022. Natsionalnyi standart Ukrainy. URL: https://www.dec.gov.ua/wp-content/uploads/2022/08/2022_1437_smd_nv.pdf.
Qoronfleh MW, Chouchane L, Mifsud B et al. (2020). The future of medicine, healthcare innovation through precision medicine: policy case study of Qatar. Life Sciences, Society and Policy. 16: 12. https://doi.org/10.1186/s40504-020-00107-1; PMid:33129349 PMCid:PMC7603723
Shchubelka K, Turova L, Wolfsberger W et al. (2024). Genetic determinants of global developmental delay and intellectual disability in Ukrainian children. J Neurodevelop Disord 16: 13. https://doi.org/10.1186/s11689-024-09528-x; PMid:38539105 PMCid:PMC10967201
Slabkiy GО, Dudnyk SV, Shcherbinska ОS et al. (2024). Trends and structure of infant mortality in Ukraine. Ukraina. Zdorovia natsii. 2: 27-34. https://doi.org/10.32782/2077-6594/2024.2/05
Turova L, Makovetska A, Savelieva M. (2022). The synergy of the influence of polymorphic variants of the first and second phase of xenobiotic detoxification system and psycho- emotional stress on the reproductive health of a man: a literature review and a clinical case. Choloviche zdorovia, henderna ta psykhosomatychna medytsyna. 1-2: 14-15. https://doi.org/10.37321/UJMH.2022.1-2-09
Turova LO, Vezhnovets TA. (2024). Analiz kadrovoho zabezpechennia medyko-henetychnoi sluzhby v Ukraini. Klinichna ta profilaktychna medytsyna. 6: 117-125. https://doi.org/10.31612/2616-4868.6.2024.15
Vezhnovets TA, Korotkyi OV, Orabina TM, Gurianov VG, Marushko YV, Pysariev АO. (2024). Mathematical modeling of the dynamics of newborns' morbidity and mortality in Ukraine by 2026. Modern Pediatrics. Ukraine. 3(139): 37-45. https://doi.org/10.15574/SP.2024.139.37
WHO. (2010). Priorities for research on equity and health: implications for global and national priority setting and the role of WHO to take the health equity research agenda forward. Geneva. World Health Organization. URL: http://surl.li/ehetwt.
World Health Organization. (2010). Adelaide Statement on Health in All Policies: moving towards a shared governance for health and well-being. Health in All Policies International Meeting, Adelaide, Geneva. World Health Organization. URL: http://surl.li/dgahra.
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