Rare forms of eye lesions in Lyme disease in children





Lyme disease, children, borreliosis, ELISA, immunoblot, tick bite, uveitis


Lyme disease (LD) is a multisystem disease caused by Borrelia burgdorferi and other similar tick-borne borrelia.

Purpose - to analyse and present clinical cases of eye lesions in children with suspected LD for differential diagnosis and treatment refinement.

We present 2 clinical cases with ocular lesions in children of infectious genesis with suspected LD. Basic examinations, ophthalmoscopy, optical coherence tomography with angiography, clinical and immunological tests, including ELISA and immunoblot, were performed. Serological results were compared in children with different forms of eye lesions of infectious genesis.

Conclusions. The diagnosis of LD should be confirmed by laboratory tests (ELISA and western blot serological tests), indicating the presence of specific anti Borrelia burgdorferi IgM/IgG antibodies, and confirming the clinical manifestations of the disease. Paediatricians should be alert to LD, especially in residents of endemic areas. The need for prophylactic treatment of LD in children exposed to tick bites has been proven. The diagnosis of LB in children should be laboratory confirmed by a two-step method (ELISA serological tests and western blot), which confirms the clinical manifestations of the disease.

The study was performed in accordance with the principles of the Declaration of Helsinki. Informed consent of parents and child was obtained for the study.

No conflict of interests was declared by the authors.


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