Features of the modern course of granulomatosis with polyangiitis (Wegener's granulomatosis) in children on the example of a clinical case in a teenage patient

Authors

  • O.M. Okhotnikova Shupyk National Healthcare University of Ukraine, Kyiv, Ukraine https://orcid.org/0000-0003-2498-0560
  • Т.М. Tkachova Shupyk National Healthcare University of Ukraine, Kyiv, Ukraine https://orcid.org/0000-0001-8951-7767
  • Т.P. Іvanova National Children’s Specialized Hospital “OKHMATDYT” of the Ministry of Health of Ukraine, Kyiv, Ukraine
  • О.А. Oshlіanska Shupyk National Healthcare University of Ukraine, Kyiv, Ukraine https://orcid.org/0000-0002-9782-9709
  • О.І. Usova Shupyk National Healthcare University of Ukraine, Kyiv, Ukraine
  • О.V. Sharikadze Shupyk National Healthcare University of Ukraine, Kyiv, Ukraine https://orcid.org/0000-0001-7656-2307
  • О.M. Gristchenko National Children’s Specialized Hospital “OKHMATDYT” of the Ministry of Health of Ukraine, Kyiv, Ukraine
  • H.V. Shkljarska National Children’s Specialized Hospital “OKHMATDYT” of the Ministry of Health of Ukraine, Kyiv, Ukraine
  • А.Y. Denysenko National Children’s Specialized Hospital “OKHMATDYT” of the Ministry of Health of Ukraine, Kyiv, Ukraine
  • S.M. Rudenko National Children’s Specialized Hospital “OKHMATDYT” of the Ministry of Health of Ukraine, Kyiv, Ukraine
  • L.V. Semenenko National Children’s Specialized Hospital “OKHMATDYT” of the Ministry of Health of Ukraine, Kyiv, Ukraine

DOI:

https://doi.org/10.15574/SP.2023.134.149

Keywords:

Wegener’s granulomatosis, adolescent, systemic vasculitis, diagnosis, treatment, complications

Abstract

The article introduces readers to a rare disease from the group of systemic vasculitis - Wegener’s granulomatosis. The prevalence of this disease in European countries ranges from 4.9 to 10.5 cases per 1 million adult population. A feature of the disease is the pathology of the upper respiratory tract at the beginning of the inflammatory process, which leads to long and difficult treatment of patients by otolaryngologists, as a result of which the correct diagnosis is delayed and the prognosis of the disease worsens. The disease is especially rare among children.

Purpose - to share the experience of diagnosis and treatment of a teenager with this extremely rare pathology. Complications of drug therapy and ways to solve them are considered in detail.

The conclusion of this experience is an understanding of the severity of the course of the disease and the need to use aggressive therapy already in its early stages in order to save the patient’s life.

The study was conducted in accordance with the principles of the Declaration of Helsinki. Informed consent of the parents and the child was obtained for the study.

No conflict of interests was declared by the authors.

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Published

2023-10-28

Issue

No. 6(134) (2023): Modern pediatrics. Ukraine

Section

Clinical case

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