Assessment of life quality indicators in school-age children with hypertension and obesity

Authors

DOI:

https://doi.org/10.15574/SP.2023.130.50

Keywords:

quality of life, obesity, arterial hypertension, children

Abstract

The steady increase in the prevalence of obesity, arterial hypertension (Н) and their comorbidity among children and adults requires additional scientific research to identify the features of the combined course of these diseases and possible ways to improve treatment and preventive measures in patients of different age groups.

Purpose - to analyze indicators of the quality of life (QL) in school-aged children with H and obesity.

Materials and methods. 95 children aged 9-18 were examined. The examinees were divided into 4 groups: the Group 1 - children with normal blood pressure and normal body weight (BW); the Group 2 - patients with H and normal BW; the Group 3 - with normal blood pressure and obesity; the Group 4 - children with Hand obesity. QL was determined for all children using the Ukrainian version of the Pediatric Quality of Life Inventory 4.0 questionnaire. The frequency of certain complaints and some peculiarities of children’s lives in the study groups were also determined using a questionnaire developed by us. Statistical processing of the obtained results was carried out using MedStat v 5.2 (Y.E. Lyakh, V.G. Guryanov) and EZR v 1.35 (Saitama Medical Centre, Jichi Medical University, Saitama Japan 2017) programs.

Results and conclusions. QL indicators in patients with obesity and H are lower (p<0.05) than in the group of healthy children. The lowest indicators of the QL are observed in the Group 4, which were significantly lower (p<0.005) compared to the same indicators in the Groups 2 and 3.

Patients with H had significantly more frequent (p<0.05) complaints of headache and dizziness compared with the Group 1. Patients with obesity had more (p<0.05) complaints of heart palpitations during minor physical exertion compared to healthy children. In patients of the Group 4, complaints of headache, dizziness, palpitations during minor physical exertion were more common compared to the Group 1 (p<0.05), and dizziness was more common than in the Group 3 (p<0.05).

According to survey data, 44.7% of obese children estimated their body weight as normal and did not consider it appropriate to change their lifestyle.

The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of the participating institution. The informed consent of the patient was obtained for conducting the studies.

No conflict of interests was declared by the authors.

References

Álvarez J, Aguilar F, Lurbe E. (2022). Blood pressure measurement in children and adolescents: key element in the evaluation of arterial hypertension. Anales de Pediatría (English Edition). 96 (6): 536-e1. https://doi.org/10.1016/j.anpede.2022.04.011; PMid:35659490

Braunerová RT, Kunešová M, Heinen MM, Rutter H, Hassapidou M, Duleva V et al. (2021). Waist circumference and waist-to-height ratio in 7-year-old children-WHO Childhood Obesity Surveillance Initiative. Obesity reviews: an official journal of the International Association for the Study of Obesity. 22 (6): e13208. https://doi.org/10.1111/obr.13208

Chen J, Zhang S, Cui K, Liu C. (2021). Risk factors for benign paroxysmal positional vertigo recurrence: a systematic review and meta-analysis. Journal of neurology. 268 (11): 4117-4127. https://doi.org/10.1007/s00415-020-10175-0; PMid:32839838

Chen SH, Chen SC, Lai YP, Chen PH, Yeh KY. (2020). Abdominal obesity and hypertension are correlated with health-related quality of life in Taiwanese adults with metabolic syndrome. BMJ open diabetes research & care. 8 (1): e000947. https://doi.org/10.1136/bmjdrc-2019-000947; PMid:32079613 PMCid:PMC7039578

Constantinides C, Landis SH, Jarrett J, Quinn J, Ireland PJ. (2022). Quality of life, physical functioning, and psychosocial function among patients with achondroplasia: a targeted literature review. Disability and rehabilitation. 44 (21): 6166-6178. https://doi.org/10.1080/09638288.2021.1963853; PMid:34403286

CORC. (2023). Paediatric Quality of Life (PedsQL). URL: https://www.corc.uk.net/outcome-experience-measures/paediatric-quality-of-life-pedsql/

Deal BJ, Huffman MD, Binns H, Stone NJ. (2020). Perspective: Childhood Obesity Requires New Strategies for Prevention. Advances in nutrition (Bethesda, Md.). 11 (5): 1071-1078. https://doi.org/10.1093/advances/nmaa040; PMid:32361757 PMCid:PMC7490151

Drummond MD, Anthamatten A, Hande K, Choi L. (2022). Utilizing Patient Reported Outcomes and Quality of Life Measures in the Management of Obesity. Journal of doctoral nursing practice. 15 (1): 57-64. https://doi.org/10.1891/JDNP-2021-0008; PMid:35228345

Fagbohun AO, Orimadegun AE, Yaria JO, Falade AG. (2021). Obesity Affects Health-Related Quality of Life in Schools Functioning Among Adolescents in Southwest of Nigeria. Nigerian journal of clinical practice. 24 (7): 1015-1021. doi: 10.4103/njcp.njcp_490_20.

Finocchi C, Sassos D. (2017). Headache and arterial hypertension. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 38 (1): 67-72. https://doi.org/10.1007/s10072-017-2893-x; PMid:28527058

Fortini I, Felsenfeld Junior BD. (2022). Headaches and obesity. Arquivos de Neuro-Psiquiatria. 80: 204-213. https://doi.org/10.1590/0004-282x-anp-2022-s106; PMid:35976296 PMCid:PMC9491411

Gonzalo-Encabo P, Maldonado G, Valadés D, Ferragut C, Pérez-López A. (2021). The Role of Exercise Training on Low-Grade Systemic Inflammation in Adults with Overweight and Obesity: A Systematic Review. International journal of environmental research and public health. 18 (24): 13258. https://doi.org/10.3390/ijerph182413258; PMid:34948868 PMCid:PMC8703787

Haraldstad K, Wahl A, Andenæs R, Andersen JR, Andersen MH, Beisland E et al. (2019). A systematic review of quality of life research in medicine and health sciences. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. 28 (10): 2641-2650. https://doi.org/10.1007/s11136-019-02214-9; PMid:31187410 PMCid:PMC6761255

Hurianov VH, Liakh YuIe, Parii VD et al. (2018). Posibnyk z biostatystyky. Analiz rezultativ medychnykh doslidzhen u paketi EZR (R-statistics): Navchalnyi posibnyk (2018). Kyiv: Vistka: 208. URL: https://www.researchgate.net/profile/Yaroslav_Tsekhmister/publication/326271449_Posibnik_z_biostatistiki_analiz_rezultativ_medicnih_doslidzen_u_paketi_EZR_R-STATISTICS/links/5b436d09aca2728a0d664341/Posibnik-z-biostatistiki-analiz-rezultativ-medicnih-doslidzen-u-paketi-EZR-R-STATISTICS.pdf.

Jebeile H, Kelly AS, O'Malley G, Baur LA. (2022). Obesity in children and adolescents: epidemiology, causes, assessment, and management. The lancet. Diabetes & endocrinology. 10 (5): 351-365. https://doi.org/10.1016/S2213-8587(22)00047-X; PMid:35248172

Kolotkin RL, Andersen JR. (2017). A systematic review of reviews: exploring the relationship between obesity, weight loss and health-related quality of life. Clinical obesity. 7 (5): 273-289. https://doi.org/10.1111/cob.12203; PMid:28695722 PMCid:PMC5600094

Koreniev MM, Bohmat LF, Nosova OM. (2014). Arterialna hipertenziia ta ozhyrinnia v pidlitkiv. Ukrainskyi zhurnal dytiachoi endokrynolohii. 2: 79-80. URL: http://nbuv.gov.ua/UJRN/ujde_2014_2_23.

Lopes AR, Moreira MD, Trelha CS, Marchiori LL. (2013). Association between complaints of dizziness and hypertension in non-institutionalized elders. International archives of otorhinolaryngology. 17 (2): 157-162. https://doi.org/10.7162/S1809-97772013000200007; PMid:25992007 PMCid:PMC4423284

Lurbe E, Agabiti-Rosei E, Cruickshank JK, Dominiczak A, Erdine S, Hirth A et al. (2016). 2016 European Society of Hypertension guidelines for the management of high blood pressure in children and adolescents. Journal of hypertension. 34 (10): 1887-1920. https://doi.org/10.1097/HJH.0000000000001039; PMid:27467768

Marushko Y, Hyshchak T, Marushko T, Onufriev O, Zlobynets A, Khomych O et al. (2020). Health-related quality of life in pediatric patients with high-normal blood pressure and primary arterial hypertension. Family Medicine & Primary Care Review. 22 (4): 291-296. https://doi.org/10.5114/fmpcr.2020.100433

Marushko Y, Kostynska N, Hyshchak T. (2021). Exercise tolerance of school-age children with hypertension, considering body weight. Zaporozhye Medical Journal. 23 (4): 509-515. https://doi.org/10.14739/2310-1210.2021.4.227348

Marushko YuV, Hyshchak TV, Marushko TV, Kostynska NH, Khomych OV. (2023). Henderni osoblyvosti pokaznykiv yakosti zhyttia, poviazanoi zi zdoroviam, u ditei z vysokym normalnym arterialnym tyskom i pervynnoiu arterialnoiu hipertenziieiu. Zdorove rebenka. 2: 35.

Marushko YV, Hyshchak TV, Kostynska NG. (2022). Research of body weight, height and waist circumference in children of Kyiv at the present stage. Modern Pediatrics. Ukraine. 5 (125): 60-68. https://doi.org/10.15574/SP.2022.125.60

Marushko YV, Zlobynets AS, Hychka SH, Hyshchak TV, Khomych OV, Hrynevych IV. (2020). Clinical, instrumental and morphological parallels in combination of chronic gastroduodenitis and primary hypertension in children. Zaporozhye Medical Journal. 22 (3): 350-355. https://doi.org/10.14739/2310-1210.2020.3.204918

Meena J, Singh M, Agarwal A, Chauhan A, Jaiswal N. (2021). Prevalence of Hypertension among Children and Adolescents in India: A Systematic Review and Meta-Analysis. Indian journal of pediatrics. 88 (11): 1107-1114. https://doi.org/10.1007/s12098-021-03686-9; PMid:33796994

Morales-Estrella JL, Ciftci FD, Trick WE, Hinami K. (2017). Physical symptoms screening for cardiopulmonary complications of obesity using audio computer-assisted self-interviews. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. 26 (8): 2085-2092. https://doi.org/10.1007/s11136-017-1549-x; PMid:28315177

MOZ Ukrainy. (2018). Statystychno-analitychnyi dovidnyk z dytiachoi endokrynolohii za 2017 rik. URL: http://medstat.gov.ua/ukr/MMXVII.html.

Nittari G, Scuri S, Petrelli F, Pirillo I, Di Luca NM, Grappasonni I. (2019). Fighting obesity in children from European world health organization member states. Epidemiological data, medicalsocial aspects, and prevention programs. La Clinica Terapeutica. 170 (3): e223-e230. doi: 10.7417/CT.2019.2137.

Payne ME, Porter Starr KN, Orenduff M, Mulder HS, McDonald SR, Spira AP, Pieper CF, Bales CW. (2018). Quality of Life and Mental Health in Older Adults with Obesity and Frailty: Associations with a Weight Loss Intervention. The journal of nutrition, health & aging. 22 (10): 1259-1265. https://doi.org/10.1007/s12603-018-1127-0; PMid:30498835 PMCid:PMC6444357

Petek T, Hertiš T, Varda NM. (2018). Health-related quality of life in paediatric arterial hypertension: a cross-sectional study. BMC pediatrics. 18 (1): 146. https://doi.org/10.1186/s12887-018-1120-0; PMid:29716573 PMCid:PMC5930650

Sagar R, Gupta T. (2018). Psychological Aspects of Obesity in Children and Adolescents. Indian journal of pediatrics. 85 (7): 554-559. https://doi.org/10.1007/s12098-017-2539-2; PMid:29150753

Song P, Zhang Y, Yu J, Zha M, Zhu Y, Rahimi K, Rudan I. (2019). Global Prevalence of Hypertension in Children: A Systematic Review and Meta-analysis. JAMA pediatrics. 173 (12): 1154-1163. https://doi.org/10.1001/jamapediatrics.2019.3310; PMid:31589252 PMCid:PMC6784751

Stephenson J, Smith CM, Kearns B, Haywood A, Bissell P. (2021). The association between obesity and quality of life: a retrospective analysis of a large-scale population-based cohort study. BMC public health. 21 (1): 1990. https://doi.org/10.1186/s12889-021-12009-8; PMid:34732156 PMCid:PMC8567540

Stierman B, Afful J, Carroll MD, Chen TC, Davy O, Fink S et al. (2021). National Health and Nutrition Examination Survey 2017 - March 2020 prepandemic data files development of files and prevalence estimates for selected health outcomes. National Health Statistics Reports. Series NHSR No. 158. https://doi.org/10.15620/cdc:106273

Styne DM, Arslanian SA, Connor EL, Farooqi IS, Murad MH, Silverstein JH, Yanovski, JA. (2017). Pediatric Obesity-Assessment, Treatment, and Prevention: An Endocrine Society Clinical Practice Guideline. The Journal of clinical endocrinology and metabolism. 102 (3): 709-757. https://doi.org/10.1210/jc.2016-2573; PMid:28359099 PMCid:PMC6283429

Taşdemir M, Erginöz E, Gayret ÖB, Bilge I. (2020). Ambulatory arterial stiffness index is increased in obese children. The Turkish journal of pediatrics. 62 (2): 259-266. https://doi.org/10.24953/turkjped.2020.02.012; PMid:32419418

Tous-Espelosín M, Gorostegi-Anduaga I, Corres P, MartinezAguirre-Betolaza A, Maldonado-Martín S. (2020). Impact on Health-Related Quality of Life after Different Aerobic Exercise Programs in Physically Inactive Adults with Overweight/Obesity and Primary Hypertension: Data from the EXERDIET-HTA Study. International journal of environmental research and public health. 17 (24): 9349. https://doi.org/10.3390/ijerph17249349; PMid:33327586 PMCid:PMC7765072

Westgate CSJ, Israelsen IME, Jensen RH, Eftekhari S. (2021). Understanding the link between obesity and headache-with focus on migraine and idiopathic intracranial hypertension. The Journal of Headache and Pain. 22 (1): 1-12. https://doi.org/10.1186/s10194-021-01337-0; PMid:34629054 PMCid:PMC8504002

Published

2023-03-28

Issue

Section

Original articles