The role of azithromycin in the antibacterial therapy of acute respiratory infections in children


  • S.O. Kramarov Bogomolets National Medical University, Kyiv, Ukraine, Ukraine
  • V.V. Yevtushenko Bogomolets National Medical University, Kyiv, Ukraine, Ukraine



antibiotics, acute respiratory infection, macrolides, azithromycin, children


Acute respiratory infections are the leading cause of morbidity and mortality in childhood. Antibacterial therapy for acute respiratory infections should be prescribed carefully and under strict indications.

This review analyzes the etiological structure of diseases of the upper and lower respiratory tract, identifies modern views on the rational use of antibacterial agents in diseases such as acute tonsillopharyngitis, rhinosinusitis, bronchitis and pneumonia. Among the variety of antibacterial agents, macrolide drugs, in particular azithromycin, are most often used in pediatric practice. The pharmacological properties of azithromycin, mechanisms of its antimicrobial and immunomodulatory activity, indications for use in acute respiratory infections in children are considered in the article.

No conflict of interest was declared by the authors.


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