Iodine deficiency during lactation: why supplementation is so important?
Keywords:
iodine deficiency diseases, brain maturation, supplementation, lactating mother, infantAbstract
Iodine deficiency has multiply of adverse effectes in the human organism, which are termed «iodine deficiency disorders» (IDD). Iodine deficiency disorders are one of the most prevalent alimentary-dependent diseases in population. Adequate iodine consumption during fetal development and in early childhood contribute to the brain maturation, development of associative connections and myelination of nerve fibers; improve cognitive functions of the child. The iodized salt usage is the effective approach in children and adults, but has limitations in pregnant, lactating mothers and young children. In these groups of population, the supplementation with potassium iodide drugs is recommended: pregnant and lactating women have to supply in addition to the diet 200 μg of iodine every day. In the second half of the 1-st year of life the total volume of breast milk in baby's diet decreases, so the fortification of complementary foods with potassium iodide recommended: 50 μg of iodine can be added to any meal.References
Belyih NA. (2016). Otsenka vliyaniya perinatalnyih faktorov i profilakticheskih meropriyatiy na soderzhanie yoda i zheleza v grudnom moloke. Voprosyi detskoy dietologiiTekst dlya perevoda. 14;3: 10-14.
Andersson M, De Benoist B, Delange F, Zupan J. (2007). Prevention and control of iodine deficiency in pregnant and lactating women and in children less than 2-years-old: conclusions and recommendations of the Technical Consultation. Public Health Nutrition. 10(12A): 1606–1611. https://doi.org/10.1017/S1368980007361004; PMid:18053287
Andersson M, Karumbunathan V, Zimmermann M. (2012). Global Iodine Status in 2011 and Trends over the Past Decade. J Nutr. 142;4: 744–750. https://doi.org/10.3945/jn.111.149393; PMid:22378324
Azizi F, Smyth P. (2009). Breastfeeding and maternal and infant iodine nutrition. Clin Endocrinol. 70;5: 803–809. https://doi.org/10.1111/j.1365-2265.2008.03442.x; PMid:19178515
Becker DV, Braverman LE, Delange F, Dunn JT et al. (2006). Iodine supplementation for pregnancy and lactation — United States and Canada: recommendations of the American Thyroid Association. Thyroid. 16;10: 949–951. https://doi.org/10.1089/thy.2006.16.949; PMid:17042677
Bouhouch RR, Bouhouch S, Cherkaoui M, Aboussad A. et al. (2014). Direct Iodine Supplementation of Infants Versus Supplementation of Their Breastfeeding Mothers: a DoubleBlind, Randomised, Placebo-Controlled Trial. Lancet Diabetes Endocrinol. 2;3: 197–209. https://doi.org/10.1016/S2213-8587(13)70155-4
Delange F. (2004). Optimal Iodine Nutrition during Pregnancy, Lactation and the Neonatal Period. Int J Endocrinol Metab. 2: 1–12.
De-Regil LM, Harding KB, PenaRosal GP. (2015). Iodine Supplementation for Women During the Preconception, Pregnancy and Postpartum Period (Protocol). Cochrane Database of Systematic Reviews. Issue 6. Art. No.CD011761. https://doi.org/10.1002/14651858.CD011761
Fiengold SB, Brawn RS. (2010). Neonatal Thyroid Function. Neo Reviews. 11;11: 640–645. https://doi.org/10.1542/neo.11-11-e640
Henrichs J, Bongers-Schokking JJ, Schenk JJ, Ghassabian A et al. (2010). Maternal thyroid function during early pregnancy and cognitive functioning in early childhood: the generation study. Journal of Clinical Endocrinology and Metabolism. 95;9: 4227–4234. https://doi.org/10.1210/jc.2010-0415; PMid:20534757
Jorgensen A, O'Leary P, James I, Skea S, Sherriff J. (2016). Assessment of Breast Milk Iodine Concentrations in Lactating Women in Western Australia. Nutrients. 8: 699–706. https://doi.org/10.3390/nu8110699; PMid:27827913 PMCid:PMC5133086
Leung AM, Pearce EN, Braverman LE. (2011). Iodine Nutrition in Pregnancy and Lactation. Endocrinol Metab Clin North Am. 40;4: 765–777. https://doi.org/10.1016/j.ecl.2011.08.001; PMid:22108279 PMCid:PMC3266621
WHO. (2007). Assessment of the Iodine Deficiency Disorders and monitoring their elimination: a guide for programmer managers. 3rd ed. Geneva: 98.
Zhou SG, Anderson AG, Gibson RA, Makrides M. (2013). Effect of Iodine Supplementation in Pregnancy on Child Development and other Clinical Outcomes: a Systematic Review and Randomized Controlled Trials. Am J Clin Nutr. 98: 1241–1254. https://doi.org/10.3945/ajcn.113.065854; PMid:24025628
Zimmermann MB. (2012). The Effects of Iodine Deficiency in Pregnancy and Infancy. Pediatric and Perinatal. Epidemiology. 26: 108–117. https://doi.org/10.1111/j.1365-3016.2012.01275.x; PMid:22742605
Downloads
Issue
Section
License
The policy of the Journal “MODERN PEDIATRICS. UKRAINE” is compatible with the vast majority of funders' of open access and self-archiving policies. The journal provides immediate open access route being convinced that everyone – not only scientists - can benefit from research results, and publishes articles exclusively under open access distribution, with a Creative Commons Attribution-Noncommercial 4.0 international license (СС BY-NC).
Authors transfer the copyright to the Journal “MODERN PEDIATRICS. UKRAINE” when the manuscript is accepted for publication. Authors declare that this manuscript has not been published nor is under simultaneous consideration for publication elsewhere. After publication, the articles become freely available on-line to the public.
Readers have the right to use, distribute, and reproduce articles in any medium, provided the articles and the journal are properly cited.
The use of published materials for commercial purposes is strongly prohibited.