Chickenpox and streptococcal infection: a clinical example of the combined course of chickenpox and scarlet fever

Authors

  • O.V. Usachova Zaporizhzhya State Medical University, Ukraine
  • E.A. Silina Zaporizhzhya State Medical University, Ukraine
  • T.M. Pakholchuk Zaporizhzhya State Medical University, Ukraine
  • O.V. Konakova Zaporizhzhya State Medical University, Ukraine
  • O.A. Dralova Zaporizhzhya State Medical University, Ukraine

Keywords:

children, chicken pox, bacterial complications, scarlet fever

Abstract

Chicken pox today is an important medical and social problem because with this disease it is possible to develop complications due to both the direct action of the virus and the addition of a secondary bacterial infection. Forms of chickenpox complicated by a bacterial infection were recorded in 56 (16.0%) of all treated patients in the Zaporozhye region. Among the complications, pyoderma was more common in 24 children (42.8%), pneumonia was recorded in 13 (23.2%), lymphadenitis in 5 (8.9%), acute tonsillitis in 4 (7.1%), average purulent otitis media in 3 (5.4%), mucopurulent conjunctivitis, blepharitis in 3 (5.4%), phlegmon in 2 (3.6%). Two children (3.6%) reported a combined course of chickenpox and scarlet fever.

Purpose — to demonstrate, with the example of a clinical case of the course of super0infection — chickenpox and scarlet fever in a child, to show the features of this course and the difficulties of diagnosis.

Сlinical case. Clinical and laboratory surveillance of a 110year0old child was received, which was treated in a hospital for atypical course of chickenpox for 20 days. A clinical case of the atypical course of chickenpox in a child is described, which was regarded as superinfection with aggressive bacterial flora, which demonstrates the possibility of developing a generalized form of streptococcal infection (scarlet fever) as superinfection in chickenpox, indicates the need for a kind of diagnosis of chickenpox, the importance of the doctor's alertness regarding the attachment of a bacterial infection in such a case and the feasibility of vaccinating against chickenpox for each child.

The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of these Institutes. The informed consent of the patient was obtained for conducting the studies.

 

References

Blumental S, Sabbe M, Lepage P. (2016, Jan). Belgian Group for Varicella. Varicella paediatric hospitalisations in Belgium: a 1-year national survey. Arch Dis Child. 101 (1): 16–22. https://doi.org/10.1136/archdischild-2015-308283; PMid:26130380 PMCid:PMC4717424. Epub 2015 Jan 30.

Derzhavnyi ekspertnyi tsentr MOZ Ukrainy; Natsionalna medychna akademiia pisliadyplomnoi osvity imeni P.L. Shupyka; Natsionalnyi medychnyi universytet imeni O.O. Bohomoltsia; Vyshchyi derzhavnyi navchalnyi zaklad Ukrainy «Bukovynskyi derzhavnyi medychnyi universytet»; Ukrainska asotsiatsiia simeinoi medytsyny; Vseukrainska asotsiatsiia infektsionistiv. (2016). Vitriana vispa. Klinichna nastanova. URL: http://mtd.dec.gov.ua/images/dodatki/KN/AKN_VV.pdf.

DU «Zaporizkyi oblasnyi laboratornyi tsentr Ministerstva okhorony zdorovia Ukrainy». (2020). Stan infektsiinoi zakhvoriuvanosti. URL: http://www.oblses.zp.ua/index.php?70.

Dulovie O, Gvozdenovie E, Nikolie J, Spurnie AR, Katanie N, Kovarevie Pavieevie D. (2010). Varicella complications: is it time to consider a rou tine varicella vaccination? Vojnosanit Pregl. 67 (7): 523529. https://doi.org/10.2298/VSP1007523D; PMid:20707045.

Hecht J, Siedler A. (2017). The epidemiology of varicella disease in Germany after introduction of a vaccination recommendation: analysis of mandatory and sentinel data between 2002 and 2014. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 60: 118–126. https://doi.org/10.1007/s00103-016-2475-8; PMid:27878603.

Kramarov SO, Vyhovska OV, Yevtushenko VV et al. (2012). Smallpox in children at the present stage. Clinical immunology. Allergology. Infectology. 53 (4): 12–15. URL: https://kiai.com.ua/ru-issue-article-753/Vitryana-vispa-u-ditey-na-suchasnomu-etapi.

MOZ Ukrainy. (2014). Pro udoskonalennia provedennia profilaktychnykh shcheplen v Ukraini. Nakaz MOZ Ukrainy vid 11.08.2014 № 551. URL: https://zakon.rada.gov.ua/laws/show/z1237-14#Text.

Nezghoda II, Levytska LI. (2017). Chickenpox in children (literature review). Infectious diseases. 1 (87): 60-70. https://doi.org/10.11603/1681-2727.2017.1.7786.

Onishchenko NV, Riabokon YuYu, Riabokon OV. (2018). The role of interleukin-10 gene polymorphism (rs 1800872) in the course of herpes zoster in adults. Pathologia. 15 (3): 325–329. https://doi.org/10.14739/2310-1237.2018.3.151810.

Padlipsky P, Young KD. (2018). Varicella and Zoster. Life- Threatening Rashes an Illustrated. Practical Guide. USA: Springer: 141–158. https://doi.org/10.1007/978-3-319-75623-3.

Prokopiv OV, Prykuda NM, Zadorozhnyi AM. (2016). The current state of the incidence of chicken pox in children according to the materials of Lviv region. Clinical Experimental Pathology. XV; 2 (1): 134—137.

Raulin O, Durand G, Gillet Y et al. (2010). Toxin profiling of Staphylococcus aureus strains involved in varicella superinfection. J Clin Microbiol. 48; 5: 1696–1700. https://doi.org/10.1128/JCM.02018-09; PMid:20305014 PMCid:PMC2863946.

Van Lier A, van der Maas NA, Rogerburg GD, Sanders EA, de Meiker HE. (2011). Hospitalization due to varicella in the Netherlands. BMC Infect Dis. 11: 85. https://doi.org/10.1186/1471-2334-11-85; PMid:21466668 PMCid:PMC3080814.

Published

2020-06-28