Passive smoking during pregnancy and its consequences for newborn children. сurrent state of problem (literature review)

Authors

  • T. Vanhanova Bogomolets National Medical University, Kyiv, Ukraine, Ukraine

Abstract

This literature review devoted to the pathological consequences of maternal smoking in pregnancy on the children health in the future. Modern data on the distribution of tobacco smoking in general and among certain categories of the population are given. The association of this harmful factor with a number of pathological conditions of the child, in particular prematurity, low birth weight, intrauterine growth restriction, higher risk of sudden childhood death syndrome, and higher incidence of respiratory diseases in descendants is described. Particular attention was paid to describing the role of tobacco smoke toxins in the epigenetic modification of DNA methylation processes of fetal genes, which contributes to a deeper understanding of adverse effects of smoking on people's health.

References

Global Adult Tobacco Survey — GATS. (2017). Kyiv: 240.

Abramovici A, Gandley RE, Clifton RG et al. (2015, Dec). Prenatal vitamin C and E supplementation in smokers is associated with reduced placental abruption and preterm birth: a secondary analysis. BJOG. 122(13): 1740-7.

Ashford KB, Hahn E, Hall L, Rayens MK, Noland M, Ferguson JE. (2010). The effects of prenatal secondhand smoke exposure on preterm birth and neonatal outcomes. J Obstet Gynecol Neonatal Nurs. 39: 525—535. https://doi.org/10.1111/j.1552-6909.2010.01169.x; PMid:20919999 PMCid:PMC2951268

Bauer T, Trump S, Ishaque N. (2016, Mar 24). Environment4induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children. Mol Syst Biol.12(3): 861. https://doi.org/10.15252/msb.20156520; PMid:27013061 PMCid:PMC4812527

Been JV, Nurmatov UB, Cox B, Nawrot TS, van Schayck CP, Sheikh A. (2014, May 3). Effect of smoke-free legislation on perinatal and child health: a systematic review and meta analysis. Lancet.383(9928): 1549—60. https://doi.org/10.1016/S0140-6736(14)60082-9

Bierut LJ. (2010, Jan). Review. Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15-q24-25. Trends Pharmacol Sci.31(1): 46—51. https://doi.org/10.1016/j.tips.2009.10.004; PMid:19896728 PMCid:PMC2993565

Bjerg A, Hedman L, Perzanowski M, Lundback B, Ronmark E. (2011, Apr). A strong synergism of low birth weight and prenatal smoking on asthma in schoolchildren. Pediatrics.127(4): e905—12. https://doi.org/10.1542/peds.2010-2850; PMid:21422092 PMCid:PMC3387890

Caleyachetty R, Tait CA, Kengne AP et al. (2014, Sep). Tobacco use in pregnant women: analysis of data from Demographic and Health Surveys from 54 low-income and middle-income countries. Lancet Glob Health.2(9): e513-e520. https://doi.org/10.1016/S2214-109X(14)70283-9

Chamberlain C, O'Mara-Eves A, Oliver S et al. (2017, Feb 14). Review Psychosocial interventions for supporting women to stop smoking in pregnancy. Cochrane Database Syst Rev.2: CD001055. https://doi.org/10.1002/14651858.CD001055.pub5; PMid:28196405 PMCid:PMC6472671

Cunningham J, Dockery DW, Speizer FE. (1994, Jun 15). Maternal smoking during pregnancy as a predictor of lung function in children. Am J Epidemiol. 139(12): 1139—52. https://doi.org/10.1093/oxfordjournals.aje.a116961; PMid:8209873

Filion KB, Abenhaim HA, Mottillo S et al. (2011, Nov). The effect of smoking cessation counselling in pregnant women: a meta-analysis of randomised controlled trials. BJOG.118(12): 1422—8. https://doi.org/10.1111/j.1471-0528.2011.03065.x; PMid:21880109

Fu XW, Wood K, Spindel ER. (2011, Feb). Prenatal nicotine exposure increases GABA signaling and mucin expression in airway epithelium. Am J Respir Cell Mol Biol.44(2): 222—9. https://doi.org/10.1165/rcmb.2010-0109OC; PMid:20448051 PMCid:PMC3049233

Gavarkovs AG, Risica PM, Parker DR, Jennings E, Mello J, Phipps M. (2018). Self-Reported Environmental Tobacco Smoke Exposure and Avoidance Compared with Cotinine Confirmed Tobacco Smoke Exposure among Pregnant Women and Their Infants. Int J Environ Res Public Health. 15(5): 871. https://doi.org/10.3390/ijerph15050871; PMid:29702552 PMCid:PMC5981910

Hafen G, Trachsel D. (2010). Tabagisme et tabagisme passif durant l'enfance Acta Paediatr. 21; 4.

Hawsawi A, Bryant L, Goodfellow L. (2015, Jan). Association between exposure to secondhand smoke during pregnancy and low birthweight: a narrative review. Respir Care.60(1): 135—40. https://doi.org/10.4187/respcare.02798; PMid:25006271

Hayatbakhsh M, Sadasivam S, Mamun A, Najman J, Williams G, O'Callaghan M. (2009, Sep). Maternal smoking during and after pregnancy and lung function in early adulthood: a prospective study. Thorax. 64(9): 810—4. https://doi.org/10.1136/thx.2009.116301; PMid:19525264

Hayes C, Kearney M, O'Carroll H et al. (2016, Oct 29). Patterns of Smoking Behaviour in Low-Income Pregnant Women: A Cohort Study of Differential Effects on Infant Birth Weight. Int J Environ Res Public Health.13(11). https://doi.org/10.3390/ijerph13111060; PMid:27801861 PMCid:PMC5129270

Herberth G, Bauer M, Gasch M et al. (2014). Maternal and cord blood miR-223 expression associates with prenatal tobacco smoke exposure and low regulatory T-cell numbers. J Allergy Clin Immunol. 133: 543—550. https://doi.org/10.1016/j.jaci.2013.06.036; PMid:23978443

IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Tobacco smoke and involuntary smoking. (2004). IARC Monogr Eval Carcinog Risks Hum.83: 1—1438.

Ion R, Bernal AL. (2015, Aug). Review. Smoking and Preterm Birth. Reprod Sci. 22(8): 918—26. https://doi.org/10.1177/1933719114556486; PMid:25394641

Jaddoe VW, Troe EJ, Hofman A et al. (2008, Mar). Active and passive maternal smoking during pregnancy and the risks of low birthweight and preterm birth: the Generation R Study. Paediatr Perinat Epidemiol.22(2): 162—71. https://doi.org/10.1111/j.1365-3016.2007.00916.x; PMid:18298691

Kawashima A, Koide K, Ventura W et al. (2014). Effects of maternal smoking on the placental expression of genes related to angiogenesis and apoptosis during the first trimester.PLoS One.9(8): e106140. https://doi.org/10.1371/journal.pone.0106140; PMid:25165809 PMCid:PMC4148425

Leermakers ET, Taal HR, Bakker R et al. (2012). A common genetic variant at 15q25 modifies the associations of maternal smoking during pregnancy with fetal growth: the generation R study. PLoS One.7(4): e34584. https://doi.org/10.1371/journal.pone.0034584; PMid:22496830 PMCid:PMC3319619

Leonardi4Bee J, Britton J, Venn A. (2011). Secondhand smoke and adverse fetal outcomes in nonsmoking pregnant women: A meta-analysis.Pediatrics.127: 734—741. https://doi.org/10.1542/peds.2010-3041; PMid:21382949

Liu W, Huang C, Cai J et al. (2018, Feb 15). Household environmental exposures during gestation and birth outcomes: A cross-sectional study in Shanghai, China. Sci Total Environ.615: 1110—1118. https://doi.org/10.1016/j.scitotenv.2017.10.015; PMid:29751416

Li YF, Gilliland FD, Berhane K et al. (2000, Dec). Effects of in utero and environmental tobacco smoke exposure on lung function in boys and girls with and without asthma. Am J Respir Crit Care Med.162(6): 2097—104. https://doi.org/10.1164/ajrccm.162.6.2004178; PMid:11112121

Lustre BL, Dixon CA, Merianos AL et al. (2016). Assessment of tobacco smoke exposure in the pediatric emergency department.Prev Med.85: 42—46. https://doi.org/10.1016/j.ypmed.2016.01.003; PMid:26794047 PMCid:PMC4801706

Magnus MC, Tapia G, Olsen SF et al. (2018, Nov). Parental Smoking and Risk of Childhood-onset Type 1 Diabetes. Epidemiology. 29(6): 848—856. https://doi.org/10.1097/EDE.0000000000000911; PMid:30074542

Martinez FD. (2009, May 1). Review The origins of asthma and chronic obstructive pulmonary disease in early life. Proc Am Thorac Soc.6(3): 272—7. https://doi.org/10.1513/pats.200808-092RM; PMid:19387029 PMCid:PMC2677402

McEvoy CT, Milner KF, Scherman AJ et al. (2017, Jul). Vitamin C to Decrease the Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP): Rationale, design, and methods of a randomized, controlled trial of vitamin C supplementation in pregnancy for the primary prevention of effects of in utero tobacco smoke exposure on infant lung function and respiratory health Contemp Clin Trials.58: 66—77. https://doi.org/10.1016/j.cct.2017.05.008; PMid:28495620 PMCid:PMC5696784

McEvoy CT, Spindel ER. (2017, Jan). Pulmonary Effects of Maternal Smoking on the Fetus and Child: Effects on Lung Development, Respiratory Morbidities, and Life Long Lung Health. Paediatr Respir Rev.21: 27—33. https://doi.org/10.1016/j.prrv.2016.08.005; PMid:27639458 PMCid:PMC5303131

Medley N, Vogel JP, Care A, Alfirevic Z. (2018, Nov 14). Interventions during pregnancy to prevent preterm birth: an overview of Cochrane systematic reviews. Cochrane Database Syst Rev.11: CD012505. https://doi.org/10.1002/14651858.CD012505.pub2; PMid:30480756

Neuman A, Hohmann C, Orsini N et al. (2012, Nov 15). Maternal smoking in pregnancy and asthma in preschool children: a pooled analysis of eight birth cohorts. Am J Respir Crit Care Med.186(10): 1037—43. https://doi.org/10.1164/rccm.201203-0501OC; PMid:22952297

Peters JL, Boynton4Jarrett R, Sandel M. (2013, Apr). Prenatal environmental factors influencing IgE levels, atopy and early asthma. Curr Opin Allergy Clin Immunol.13(2): 187—92. https://doi.org/10.1097/ACI.0b013e32835e82d3; PMid:23385288

Rauh VA, Whyatt RM, Garfinkel R et al. (2017, Jan). A tailored video intervention to reduce smoking and environmental tobacco exposure during and after pregnancy: Rationale, design and methods of Baby's Breath. Contemp Clin Trials.52: 1—9. https://doi.org/10.1016/j.cct.2016.10.010; PMid:27818283

Rotroff DM, Joubert BR, Marvel SW et al. (2016, Nov 25). Maternal smoking impacts key biological pathways in newborns through epigenetic modification in Utero. BMC Genomics.17(1): 976. https://doi.org/10.1186/s12864-016-3310-1; PMid:27887572 PMCid:PMC5124223

Sandberg KL, Pinkerton KE, Poole SD, Minton PA, Sundell HW. (2011, Apr 30). Fetal nicotine exposure increases airway responsiveness and alters airway wall composition in young lambs. Respir Physiol Neurobiol. 176(1—2): 57—67. https://doi.org/10.1016/j.resp.2010.12.015; PMid:21195212

Sekhon HS, Jia Y, Raab R, Kuryatov A, Pankow JF, Whitsett JA, Lindstrom J, Spindel ER (1999, Mar). Prenatal nicotine increases pulmonary alpha7 nicotinic receptor expression and alters fetal lung development in monkeys. J Clin Invest. 103(5): 637—47. https://doi.org/10.1172/JCI5232; PMid:10074480 PMCid:PMC408124

Sekhon HS, Proskocil BJ, Clark JA, Spindel ER. (2004, Jun). Prenatal nicotine exposure increases connective tissue expression in foetal monkey pulmonary vessels.Eur Respir J.23(6): 906—15. https://doi.org/10.1183/09031936.04.00069604; PMid:15219006

Smedberg J, Lupattelli A, Mardby AC, Nordeng H. (2014, Jun 25). Characteristics of women who continue smoking during pregnancy: a cross4sectional study of pregnant women and new mothers in 15 European countries. BMC Pregnancy Childbirth.14: 213. https://doi.org/10.1186/1471-2393-14-213; PMid:24964728 PMCid:PMC4080751

Stayner L et al. (2007). Lung cancer risk and workplace exposure to environmental tobacco smoke. Am J Public Health. 97: 545—551. https://doi.org/10.2105/AJPH.2004.061275; PMid:17267733 PMCid:PMC1805004

Stocks J, Hislop A, Sonnappa S Review. (2013, Nov). Early lung development: lifelong effect on respiratory health and disease. Lancet Respir Med.1(9): 728—42. https://doi.org/10.1016/S2213-2600(13)70118-8

Tyrrell J, Huikari V, Christie JT et al. (2012). Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) interacts with maternal self4reported smoking status during pregnancy to influence birth weight. Hum Mol Genet. 21: 5344—5358. https://doi.org/10.1093/hmg/dds372; PMid:22956269 PMCid:PMC3516066

Vardavas CI, Hohmann C, Patelarou E et al. (2016). The independent role of prenatal and postnatal exposure to active and passive smoking on the development of early wheeze in children. Eur Respir J.48: 115—124. https://doi.org/10.1183/13993003.01016-2015; PMid:26965294

Ward C, Lewis S, Coleman T. (2007, May 16). Prevalence of maternal smoking and environmental tobacco smoke exposure during pregnancy and impact on birth weight: retrospective study using Millennium Cohort. BMC Public Health. 7: 81. https://doi.org/10.1186/1471-2458-7-81; PMid:17506887 PMCid:PMC1884144

Wenten M, Li YF, Lin PC, Gauderman WJ, Berhane K, Avol E, Gilliland FD. (2009, May). In utero smoke exposure, glutathione S-transferase P1 haplotypes, and respiratory illness-related absence among schoolchildren. Pediatrics. 123(5): 1344—51. https://doi.org/10.1542/peds.2008-1892; PMid:19403501

World Health Organization. Global Health Observatory (GHO) data: Second4hand smoke Geneva: World Health Organization. 2016. (cited 2016 June 30).

World Health Organisation. Tobacco Atlas 10. Accessed on: 01.03.2017. Available from: URL:http//:www.who.int/tobaco/en/atlas/10.pdf.

Wongtrakool C, Wang N, Hyde DM, Roman J, Spindel ER. (2012, May). Prenatal nicotine exposure alters lung function and airway geometry through α7 nicotinic receptors. Am J Respir Cell Mol Biol. 46(5): 695—702. https://doi.org/10.1165/rcmb.2011-0028OC; PMid:22246862 PMCid:PMC3359906

Zhang L, Hsia J, Tu X, Xia Y, Zhang L, Bi Z, Liu H, Li X, Stanton B. (2015, Mar 19). Exposure to secondhand tobacco smoke and interventions among pregnant women in China: a systematic review. Prev Chronic Dis.12: E35. https://doi.org/10.5888/pcd12.140377; PMid:25789496 PMCid:PMC4372160